Top flight clubs avoided upsets as six spots in the quarter finals were decided on Sunday.
Stellenbosch FC proved no walkovers as they made Amakhosi sweat.
Kaizer Chiefs have to quickly regroup in order to avoid an upset to a lower league side as they face up to Stellenbosch on Saturday.
Only 16 remain at this stage of the Nedbank Cup.
Amakhosi the overwhelming favourites to go through to the next round.
The Buccaneers will look to reassert their dominance over the Urban Warriors, following the shock defeat in their most recent league encounter.
One or two underdogs could cause an upset in the early stages of the competition.